At a national level, the central body of state administration for the cultural framework is the Ministerstvo Kultúry (Ministry of Culture) of the Slovak Republic. Its main roles are to prepare and submit legislation, to issue regulations, carry out state administration relating to culture and cultural heritage, ensure the preservation of monuments, work on international cooperation and manage public finances designated for culture. At a parliamentary level, the Výbor Národnej Rady Slovenskej Republiky pre Kultúru a Médiá (Committee of the National Council of the Slovak Republic for Culture and Media) is in charge of the cultural framework. It is responsible for implementing the government manifesto, and making recommendations on legislation.

The Ministry of Culture has 11 specialised advisory bodies such as the Central Language Council, the Council for the Preservation of Intangible Cultural Heritage, the Commission for the Preservation of Elements of Cultural Heritage, or the Monument Council, and directly manages 30 national cultural institutions. Some of the most important institutions is BIBIANA (The International House of Art for Children) and the Národné Osvetové Centrum (NOC) (National Enlightenment Center) spreading art and culture at an international and national level respectively.