At a national level, the framework for cultural policy in Luxembourg is mainly regulated by the ministère de la Culture (ministry of Culture), which is in charge of developing and implementing the government national and international cultural policy, as well as funding cultural projects. The Ministry is divided into 3 departments: the Administration and General Affairs Department, the Artistic Creation and Promotion Department, and the Cultural Heritage Department, each divided into different services. For instance, the Heritage management and awareness, the Protected area management, and the Cultural Heritage Digital Strategy Services are part of the Cultural Heritage Department.

The Government recognises 8 state cultural institutes, and cooperates with various cultural organisations attached to the central state administration, such as the Fonds Culturel National (National Cultural Fund) or the Centre culturel de rencontre Abbaye de Neumünste (Heritage Site for Culture Neumünster Abbey), which are given specific missions by the ministry. Moreover, the ministère de l’Éducation nationale, de l’Enfance et de la Jeunesse (ministry of Education, Children and Youth) and the ministère des Finances (ministry of Finance) also intervene in cultural policies.

On the legislative side, the Commission de la Culture (Commission of Culture) of the Chambre des députés (Parliament) is responsible for voting national bills and ratifying international treaties in the cultural field. It can also exert control over financial, political and administrative matters.